BDBM50242196 CHEMBL4069423

SMILES c1cc2c(cc1Cl)nc(s2)CCC(=O)O

InChI Key InChIKey=UMBLVHSXXWQLDL-UHFFFAOYSA-N

Data  2 IC50  2 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50242196   

TargetHistone deacetylase 6(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to N-terminal His6-tagged HDAC6 zinc-finger ubiquitin binding domain (1109 to 1215 residues)(unknown origin) expressed in Escherichi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to N-terminal Avi-tagged/C-terminal His6-tagged HDAC6 zinc-finger ubiquitin binding domain (1109 to 1215 residues)(unknown origin) e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataIC50: 5.50E+4nMAssay Description:Displacement of FITC-labeled RLRGG peptide from N-terminal His6-tagged HDAC6 zinc-finger ubiquitin binding domain (1109 to 1215 residues)(unknown ori...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 6(Human)
Entremed

Curated by ChEMBL
LigandPNGBDBM50242196(CHEMBL4069423)
Affinity DataIC50: 5.50E+4nMAssay Description:Displacement of N-terminal FITC-labeled RLRGG from N-terminal AviTag/C-terminal His6-tagged HDAC6 ZnF-UBD (unknown origin) expressed in Escherichia c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)