BDBM50241955 3beta-hydroxyolean-12-ene::CHEMBL455098::Germanicol::beta-amyrin

SMILES CC1(C)CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1

InChI Key InChIKey=JFSHUTJDVKUMTJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50241955   

TargetAldo-keto reductase family 1 member B1(Rat)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241955(beta-amyrin | 3beta-hydroxyolean-12-ene | Germanic...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of aldose reductase in rat lens homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241955(beta-amyrin | 3beta-hydroxyolean-12-ene | Germanic...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human GST-tagged PTP1B catalytic domain expressed in Escherichia coli BL21 using para-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
University of Illinois

Curated by ChEMBL
LigandPNGBDBM50241955(beta-amyrin | 3beta-hydroxyolean-12-ene | Germanic...)
Affinity DataIC50: 4.68E+5nMAssay Description:Inhibition of HIV1 RTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50241955(beta-amyrin | 3beta-hydroxyolean-12-ene | Germanic...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50241955(beta-amyrin | 3beta-hydroxyolean-12-ene | Germanic...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli using arachidonic acid as substrate preincubated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50241955(beta-amyrin | 3beta-hydroxyolean-12-ene | Germanic...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
Osaka University

Curated by ChEMBL
LigandPNGBDBM50241955(beta-amyrin | 3beta-hydroxyolean-12-ene | Germanic...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant N-terminal His-tagged 15-LOX2 expressed in Escherichia coli using arachidonic acid as substrate preincubated for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed