BDBM50241718 CHEMBL1354522

SMILES Fc1cccc(Cl)c1CNc1nc(n[nH]1)-c1ccco1

InChI Key InChIKey=AHOHWELPUXLPOF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50241718   

TargetTyrosine-protein kinase Lyn(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50241718(CHEMBL1354522)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human LYN using TK-substrate-biotin after 40 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50241718(CHEMBL1354522)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of His-tagged full length recombinant human BMX expressed in baculovirus expression system using TK-substrate-biotin after 40 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50241718(CHEMBL1354522)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of human N-terminal His-tagged BTK expressed in bacmid transfected Sf21 insect cells using TK-substrate-biotin after 40 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50241718(CHEMBL1354522)
Affinity DataIC50: 531nMAssay Description:Inhibition of His-tagged full length recombinant human LCK expressed in baculovirus expression system using TK-substrate-biotin after 40 mins by HTRF...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50241718(CHEMBL1354522)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human N-terminal His-tagged p38alpha expressed in Escherichia coli BL21 DE3 using Ser/Thr-15 peptide as substrate after 60 mins by Z'-L...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
National Institute of Biological Sciences, Beijing

Curated by ChEMBL
LigandPNGBDBM50241718(CHEMBL1354522)
Affinity DataIC50: 600nMAssay Description:Inhibition of C-terminal His-tagged full length recombinant human FYN expressed in baculovirus expression system using TK-substrate-biotin after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2019
Entry Details Article
PubMed