BDBM50241296 CHEMBL245412::Zerumbone

SMILES C\C1=C/CC(C)(C)\C=C\C(=O)\C(C)=C\CC1

InChI Key InChIKey=GIHNTRQPEMKFKO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241296   

TargetCytochrome P450 3A4(Human)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241296(Zerumbone | CHEMBL245412)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human CYP3A4 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241296(Zerumbone | CHEMBL245412)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2D6 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetZinc finger protein GLI1(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50241296(Zerumbone | CHEMBL245412)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Gli1-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetZinc finger protein GLI2(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50241296(Zerumbone | CHEMBL245412)
Affinity DataIC50: 910nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed