BDBM50240875 CHEMBL4080323

SMILES Cc1cnc(c(c1OC)C)Cn2c3c(cn2)c(nc(n3)N)Cl

InChI Key InChIKey=IKGRZHVFOMUXCQ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240875   

TargetHeat shock protein 75 kDa, mitochondrial(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandPNGBDBM50240875(CHEMBL4080323)
Affinity DataIC50: 138nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant human N-terminal His6-tagged TRAP1 (60 to 561 residues) expressed in Escherichia coli BL21(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Ulsan National Institutes of Science and Technology (Unist)

Curated by ChEMBL
LigandPNGBDBM50240875(CHEMBL4080323)
Affinity DataIC50: 97nMAssay Description:Inhibition of FITC3-labeled PU-H71 binding to recombinant HSP90alpha (unknown origin) after 24 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2019
Entry Details Article
PubMed