BDBM50240779 CHEMBL4067871

SMILES OC[C@H](Nc1cnc(-c2cc(Cl)ccc2O)c(c1)-c1ccc2cnccc2c1)c1ccccc1

InChI Key InChIKey=UMBIRSZUCJNBHB-UHFFFAOYSA-N

Data  30 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 30 hits for monomerid = 50240779   

TargetMast/stem cell growth factor receptor Kit(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant c-Kit (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant ALK (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant ErbB2 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant Tyro3 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant IGF1R (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetInsulin receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 431nMAssay Description:Inhibition of recombinant IR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant VEGFR-1 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human FGFR3 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant c-Src (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant ErbB4 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of recombinant ABL (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant AXL (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 196nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Erk2 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK4 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant EPH-A2 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase ROS(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 169nMAssay Description:Inhibition of recombinant ROS1 (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetLeukocyte tyrosine kinase receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant LTK (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FGFR2 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 249nMAssay Description:Inhibition of FGFR2 in human SNU16 cells assessed as inhibition of cell proliferation after 72 hrs by cell counting kit-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of recombinant Mer (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant PDGFR-beta (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant PDGFR-alpha (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 0.0400nMAssay Description:Inhibition of recombinant Ret (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of recombinant KDR (unknown origin) using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 4(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of recombinant human FGFR4 using poly (Glu,Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50240779(CHEMBL4067871)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CDK6 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2019
Entry Details Article
PubMed