BDBM50240370 1-(2-(allyloxy)phenoxy)-3-(isopropylamino)propan-2-ol::1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol::1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol (Oxprenolol)::1-(2-Allyloxy-phenoxy)-3-isopropylamino-propan-2-ol(oxprenolol)::CHEMBL546::OXPRENOLOL::Trasicor

SMILES CC(C)NCC(O)COc1ccccc1OCC=C

InChI Key InChIKey=CEMAWMOMDPGJMB-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50240370   

TargetSolute carrier family 22 member 1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50240370(CHEMBL546 | 1-(2-Allyloxy-phenoxy)-3-isopropylamin...)
Affinity DataIC50: 2.86E+4nMAssay Description:Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50240370(CHEMBL546 | 1-(2-Allyloxy-phenoxy)-3-isopropylamin...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50240370(CHEMBL546 | 1-(2-Allyloxy-phenoxy)-3-isopropylamin...)
Affinity DataKi:  7.76nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50240370(CHEMBL546 | 1-(2-Allyloxy-phenoxy)-3-isopropylamin...)
Affinity DataKi:  9.77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50240370(CHEMBL546 | 1-(2-Allyloxy-phenoxy)-3-isopropylamin...)
Affinity DataKi:  93nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Niigata College of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50240370(CHEMBL546 | 1-(2-Allyloxy-phenoxy)-3-isopropylamin...)
Affinity DataKi:  174nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed