BDBM50239391 2-Mercapto-Benzoic Acid::CHEBI:59124::THIOSALICYLIC ACID

SMILES c1ccc(c(c1)C(=O)O)S

InChI Key InChIKey=NBOMNTLFRHMDEZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239391   

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50239391(THIOSALICYLIC ACID | CHEBI:59124 | 2-Mercapto-Benz...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50239391(THIOSALICYLIC ACID | CHEBI:59124 | 2-Mercapto-Benz...)
Affinity DataEC50:  1.69E+4nMAssay Description:Substrate-dependent activation of HDAC8 (unknown origin) using FLUOR DE LYS as substrate incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed