BDBM50234907 CHEMBL4101534

SMILES CCc1cc(O)ccc1-c1ccc2c(n[nH]c2c1)C(=O)Nc1ccc(C)nc1

InChI Key InChIKey=CUKXYSDQFPFABZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234907   

TargetTyrosine-protein kinase JAK1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234907(CHEMBL4101534)
Affinity DataIC50: 60nMAssay Description:Inhibition of GST tagged human recombinant JAK1 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234907(CHEMBL4101534)
Affinity DataIC50: 59nMAssay Description:Inhibition of GST tagged human recombinant JAK2 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMed
LigandPNGBDBM50234907(CHEMBL4101534)
Affinity DataIC50: 816nMAssay Description:Inhibition of Tyk2 (unknown origin) using peptide substrate preincubated for 60 mins followed by substrate addition and measured after 60 mins by mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50234907(CHEMBL4101534)
Affinity DataIC50: 418nMAssay Description:Inhibition of GST tagged human recombinant JAK3 catalytic domain expressed in baculovirus using peptide substrate preincubated for 60 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2019
Entry Details Article
PubMed