BDBM50233957 6-(2-(3-(biphenyl-4-yl)propanoyl)oxazol-5-yl)picolinic acid::6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid::CHEMBL260747

SMILES c1ccc(cc1)c2ccc(cc2)CCC(=O)c3ncc(o3)c4cccc(n4)C(=O)O

InChI Key InChIKey=VGYASWDHSIVABN-UHFFFAOYSA-N

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50233957   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50233957(6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]py...)
Affinity DataIC50: 6nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutral cholesterol ester hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50233957(6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]py...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KIAA1363More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLiver carboxylesterase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50233957(6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]py...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of TGHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50233957(6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]py...)
Affinity DataKi:  22nMpH: 9.0Assay Description:Inhibition of FAAH at pH 9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50233957(6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]py...)
Affinity DataKi:  22nMAssay Description:Inhibition of rat recombinant FAAH expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)