BDBM50226439 2-amino-6-propylpyrimidin-4(3H)-one::CHEMBL235825

SMILES CCCC1=CC(=O)NC(=N1)N

InChI Key InChIKey=FSYKBAWAYYELHH-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226439   

TargetBeta-secretase 1(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226439(2-amino-6-propylpyrimidin-4(3H)-one | CHEMBL235825)
Affinity DataKd:  4.45E+6nMAssay Description:Binding affinity to BACE1 expressed in HEK293 cells by Biocore ISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBeta-secretase 1(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226439(2-amino-6-propylpyrimidin-4(3H)-one | CHEMBL235825)
Affinity DataIC50: 2.49E+6nMAssay Description:Inhibition of human recombinant BACE1 using biotin-XSEVNLDAEFRHDSGC-Eu as substrate after 3 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)