BDBM50223783 (+)-isolariciresinol::CHEMBL399512::isolariciresinol

SMILES COc1cc2C[C@@H](CO)[C@H](CO)[C@@H](c3ccc(O)c(OC)c3)c2cc1O

InChI Key InChIKey=OGFXBIXJCWAUCH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223783   

TargetAldo-keto reductase family 1 member B1(Rat)
Kyoto Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50223783(isolariciresinol | (+)-isolariciresinol | CHEMBL39...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of aldose reductase in rat lens homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50223783(isolariciresinol | (+)-isolariciresinol | CHEMBL39...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50223783(isolariciresinol | (+)-isolariciresinol | CHEMBL39...)
Affinity DataIC50: 9.77E+4nMAssay Description:Inhibition of CYP2D6 after 30 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed