BDBM50221589 4-((6,7-dimethoxy-1,4-dihydroindeno[1,2-c]pyrazol-3-yl)ethynyl)-2-methoxyphenol::4-(6,7-dimethoxy-2,4-dihydro-indeno[1,2-c]pyrazol-3-ylethynyl)-2-methoxy-phenol::CHEMBL248396::Chk1_146

SMILES COc1cc2Cc3c(n[nH]c3C#Cc3ccc(O)c(OC)c3)-c2cc1OC

InChI Key InChIKey=MPWLZTAOZDBWMH-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221589   

LigandPNGBDBM50221589(CHEMBL248396 | Chk1_146 | 4-(6,7-dimethoxy-2,4-dih...)
Affinity DataIC50: 5nMAssay Description:Abbott Kinase Enzymatics_CHK1/289 CDC25c - IC50(uM) (IC50)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2012
Entry Details PubMed
LigandPNGBDBM50221589(CHEMBL248396 | Chk1_146 | 4-(6,7-dimethoxy-2,4-dih...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
LigandPNGBDBM50221589(CHEMBL248396 | Chk1_146 | 4-(6,7-dimethoxy-2,4-dih...)
Affinity DataKi:  5nMAssay Description:Inhibition of Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
LigandPNGBDBM50221589(CHEMBL248396 | Chk1_146 | 4-(6,7-dimethoxy-2,4-dih...)
Affinity DataKi:  5.22nMAssay Description:33P-Radiometric_Method1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2017
Entry Details
D3R