BDBM50218821 1-(5-(3-(2,4-difluorophenyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-7-carbonyl)-6-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-(3-hydroxypyrrolidin-1-yl)ethane-1,2-dione::CHEMBL244172

SMILES COc1c(cc2c(c[nH]c2n1)C(=O)C(=O)N3CC[C@H](C3)O)C(=O)N4CCn5c(cnc5c6ccc(cc6F)F)C4

InChI Key InChIKey=GRRHHDRNCLEFSY-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218821   

TargetMitogen-activated protein kinase 14(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50218821(1-(5-(3-(2,4-difluorophenyl)-5,6,7,8-tetrahydroimi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of p38-alpha MAP kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)