BDBM50216554 5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO) CYCLOPENTYL)THIOPHENE-2-CARBOXAMIDE::5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclopentyl)thiophene-2-carboxamide::CHEMBL233992

SMILES c1cc(ccc1C(=O)N[C@H]2CCC[C@H]2NC(=O)c3ccc(s3)Cl)N4C=CC=CC4=O

InChI Key InChIKey=QCPYHSAHOYXXQK-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50216554   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  7.66E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.40E+4nMAssay Description:Inhibition of human urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.50E+4nMAssay Description:Inhibition of human factor 11aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.60E+4nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >1.60E+4nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human tPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetPlasminogen(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi: >2.20E+4nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed