BDBM50208926 CHEMBL3884179

SMILES C[C@@H](c1ccc(cc1)F)N2c3c(cnc(n3)Nc4cccnc4)C(C2=O)(C)C

InChI Key InChIKey=KWJOTUQSCIOUKF-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208926   

LigandPNGBDBM50208926(CHEMBL3884179)
Affinity DataIC50: 62nMAssay Description:Inhibition of full length human MARK3 using biotin labeled peptide substrate by HTRF based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50208926(CHEMBL3884179)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MARK4 expressed in HEK293T cells coexpressing tau protein assessed as reduction in tau phosphorylation at Ser262 residues by Alph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2018
Entry Details Article
PubMed
LigandPNGBDBM50208926(CHEMBL3884179)
Affinity DataIC50: 61nMAssay Description:Inhibition of MARK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)