BDBM50208577 (R)-3-((2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl)ethynyl)quinuclidin-3-ol::(R)-3-(2-(2-benzyl-6-(3-methoxypropoxy)pyridin-3-yl)ethynyl)quinuclidin-3-ol::CHEMBL258503::ER-119884

SMILES COCCCOc1ccc(c(n1)Cc2ccccc2)C#C[C@]3(CN4CCC3CC4)O

InChI Key InChIKey=HVIKCINYHLGLMN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208577   

TargetSqualene synthase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50208577((R)-3-(2-(2-benzyl-6-(3-methoxypropoxy)pyridin-3-y...)
Affinity DataIC50: 33nMAssay Description:Inhibition of Leishmania major recombinant squalene synthase expressed in Escherichia coli by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSqualene synthase(Human)
Instituto De Parasitolog£A Y Biomedicina&Quot;L£Pez-Neyra

Curated by ChEMBL
LigandPNGBDBM50208577((R)-3-(2-(2-benzyl-6-(3-methoxypropoxy)pyridin-3-y...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)