BDBM50207717 CHEMBL3110243

SMILES CNC(=O)c1ccccc1OC2CCOCC2

InChI Key InChIKey=WZBIMVSWUWZIHN-UHFFFAOYSA-N

Data  1 IC50  4 Kd

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50207717   

TargetHistone acetyltransferase KAT2B(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50207717(CHEMBL3110243)
Affinity DataKd:  7.30E+4nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using methanol by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT2B(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50207717(CHEMBL3110243)
Affinity DataKd:  1.04E+5nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using 0.5% DMSO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT2B(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50207717(CHEMBL3110243)
Affinity DataKd:  4.59E+5nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using 3% DMSO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone acetyltransferase KAT2B(Human)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50207717(CHEMBL3110243)
Affinity DataKd:  1.66E+5nMAssay Description:Binding affinity to human His6-tagged PCAF expressed in Escherichia coli BL21(DE3)-R3 using 1% DMSO by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Cambridge

Curated by ChEMBL
LigandPNGBDBM50207717(CHEMBL3110243)
Affinity DataIC50: 3.80E+4nMAssay Description:Displacement of biotinylated H3Kac14 peptide from His6-tagged human BAZ2B expressed in Escherichia coli BL21(DE3) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)