BDBM50207361 CHEMBL3889951

SMILES CS(=O)(=O)N1CCCCC(=O)N2CCc3c2ccc(c3)Nc4ncc(c(n4)NCc5c1nccc5)C(F)(F)F

InChI Key InChIKey=FOLRUTAUDNCQAE-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207361   

TargetProtein-tyrosine kinase 2-beta(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207361(CHEMBL3889951)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of full length recombinant human N-terminal His6-tagged PYK2 expressed in baculovirus infected sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetFocal adhesion kinase 1(Human)
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50207361(CHEMBL3889951)
Affinity DataIC50: 17nMAssay Description:Inhibition of NH2-terminal His6-tagged FAK kinase domain (410 to 689 residues) (unknown origin) expressed in baculovirus infected sf9 cells using p(G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed