BDBM50200526 CHEMBL1234118

SMILES C1C[C@H]2CN[C@@H](C[C@H]2C[C@H]1CN3CC(C[C@H]3C(=O)O)(F)F)C(=O)O

InChI Key InChIKey=OXQXJYQSWZFDBB-UHFFFAOYSA-N

Data  4 KI

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200526   

TargetGlutamate receptor ionotropic, kainate 2(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50200526(CHEMBL1234118)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-kainate from human recombinant GluK2 receptor expressed in HEK293 cell membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, kainate 1(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50200526(CHEMBL1234118)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]kainate from human GluK1 expressed in HEK293 cell membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, kainate 5(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50200526(CHEMBL1234118)
Affinity DataKi:  8.90E+3nMAssay Description:Displacement of [3H]-kainate from human recombinant GluK5 receptor expressed in HEK293 cell membranes after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2018
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50200526(CHEMBL1234118)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of GluK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2019
Entry Details Article
PubMed