BDBM50197522 CHEMBL3929492

SMILES c1cc2c(cc1Cl)C=CC(=O)N2

InChI Key InChIKey=OJEBWFGRUPIVSD-UHFFFAOYSA-N

Data  1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50197522   

TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50197522(CHEMBL3929492)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibition of human factor 11a assessed as reduction in para-nitroanilide releasee using pyroGlu-Pro-Arg-pNA.HCl substrate by by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor XI(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50197522(CHEMBL3929492)
Affinity DataKi:  7.00E+4nMAssay Description:Inhibition of human factor 11a using pyroGlu-Pro-Arg-pNA.HCl substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)