BDBM50192858 CHEMBL3358966

SMILES COc1cc(cc(OC)c1OC)-c1nc(c[nH]c1=O)-c1c[nH]c2ccccc12

InChI Key InChIKey=CGXHFSJDSWAEMT-UHFFFAOYSA-N

Data  25 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50192858   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant AKT1 using GSK3/14-27 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant ARK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant SRC using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant MET using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant FAK using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CDK4/Cyclin D1 using b-CTF substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant VEGFR2 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 900nMAssay Description:Inhibition of human c-KiTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant EGFR using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CK2A1 using Casein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant B-RAF-VE using MEK1 KM substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant Aurora A using Tetra(LRRWSLG) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant PDGFRbeta using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant INSR using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of human recombinant FLT3 using poly(Ala,Glu,Lys,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PLK1 using Casein substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant EPHB4 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant IGF1R using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant VEGFR3 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant ERBB2 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant CDK2/cyclin A using histone H1 substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 8(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant COTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant Aurora B using Tetra(LRRWSLG) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50192858(CHEMBL3358966)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant TIE2 using poly(Glu,Tyr) substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2016
Entry Details Article
PubMed