BDBM50192760 CHEMBL3972392

SMILES COc1ncc(F)c(n1)N1Cc2cn(nc2[C@H]1C(C)C)-c1cccc(c1)S(C)(=O)=O

InChI Key InChIKey=HDDKTNCZLILPNB-UHFFFAOYSA-N

Data  2 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50192760   

TargetCytochrome P450 2C9(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192760(CHEMBL3972392)
Affinity DataIC50: 858nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192760(CHEMBL3972392)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192760(CHEMBL3972392)
Affinity DataEC50:  15nMAssay Description:Agonist activity at LXRbeta LBD (unknown origin) fused with Gal4-DNA binding domain expressed in HEK293 cells assessed as modulation of receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192760(CHEMBL3972392)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192760(CHEMBL3972392)
Affinity DataEC50:  491nMAssay Description:Agonist activity at LXRalpha LBD (unknown origin) fused with Gal4-DNA binding domain expressed in HEK293 cells assessed as modulation of receptor tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192760(CHEMBL3972392)
Affinity DataKi:  13nMAssay Description:Displacement of radiolabeled T0901317 from LXRbeta LBD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50192760(CHEMBL3972392)
Affinity DataKi:  136nMAssay Description:Displacement of radiolabeled T0901317 from LXRalpha LBD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2018
Entry Details Article
PubMed