BDBM50191348 (3alpha,5beta)-3-hydroxyandrostan-17-one::3alpha-etiocholanolone::3alpha-hydroxy-5beta-androstan-17-one::5-isoandrosterone::5beta-androstan-3alpha-ol-17-one::5beta-androsterone::CHEMBL85799::Etiocholanolone

SMILES C[C@]12CC[C@H]3[C@@H](CC[C@@H]4C[C@H](O)CC[C@]34C)[C@@H]1CCC2=O

InChI Key InChIKey=QGXBDMJGAMFCBF-UHFFFAOYSA-N

Data  1 KI  4 IC50  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50191348   

Target17-beta-hydroxysteroid dehydrogenase type 3(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50191348(3alpha-hydroxy-5beta-androstan-17-one | (3alpha,5b...)
Affinity DataIC50: 330nMAssay Description:Inhibitory concentration against type-3 17-beta-HSD expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50191348(3alpha-hydroxy-5beta-androstan-17-one | (3alpha,5b...)
Affinity DataIC50: 330nMAssay Description:The ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity in transfected human embryonic kidney (HEK)-293 cells experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50191348(3alpha-hydroxy-5beta-androstan-17-one | (3alpha,5b...)
Affinity DataIC50: 182nMAssay Description:The ability to inhibit the Type-3 17-beta- hydroxysteroid dehydrogenase activity in transfected human embryonic kidney (HEK)-293 cells experiment 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Human)
Laval University

Curated by ChEMBL
LigandPNGBDBM50191348(3alpha-hydroxy-5beta-androstan-17-one | (3alpha,5b...)
Affinity DataIC50: 330nMAssay Description:Inhibition of type-3 17 beta-hydroxysteroid dehydrogenase expressed in HEK293 cells at 37 degree C pH7.4 More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSex hormone-binding globulin(Human)
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM50191348(3alpha-hydroxy-5beta-androstan-17-one | (3alpha,5b...)
Affinity DataKd:  708nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50191348(3alpha-hydroxy-5beta-androstan-17-one | (3alpha,5b...)
Affinity DataEC50:  3.76E+3nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCorticosteroid-binding globulin(Human)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50191348(3alpha-hydroxy-5beta-androstan-17-one | (3alpha,5b...)
Affinity DataKi:  5.89E+3nMAssay Description:Binding affinity to human CBG receptor (corticosteroid-binding globulins)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed