BDBM50189787 CHEMBL3827178
SMILES C[C@@H](Oc1ccc2[nH]nc(-c3nc4cc(ccc4[nH]3)N3CCN(C)CC3)c2c1)c1c(Cl)cncc1Cl
InChI Key InChIKey=BAWZESLJEVSFRN-UHFFFAOYSA-N
Data 16 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50189787
TargetVascular endothelial growth factor receptor 2(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 7.5nMAssay Description:Inhibition of recombinant human VEGFR2 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 2(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FGFR2 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human FGFR3 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of recombinant human FGFR4 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human EGFR using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human ErbB2 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 782nMAssay Description:Inhibition of recombinant human PDGFRalpha using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human PDGFRbeta using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human c-Met using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human Flt1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human Flt3 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human RET using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human c-Src using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human Bcr-Abl using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human EPHA2 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Human)
East China University of Science & Technology
Curated by ChEMBL
East China University of Science & Technology
Curated by ChEMBL
Affinity DataIC50: 0.900nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu, Tyr) 4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair