BDBM50188029 3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)methyl)-1H-indol-5-yl)-2-ethoxypropanoic acid::CHEMBL209749

SMILES CCO[C@@H](Cc1ccc2c(c1)ccn2Cc3c(oc(n3)c4ccccc4Cl)C)C(=O)O

InChI Key InChIKey=PAWOPJKHTZCKMT-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50188029   

TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataEC50:  810nMAssay Description:Activity at PPARalpha by luciferase reporter gene transactivation assay relative to farglitazarMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataEC50:  760nMAssay Description:Activity at PPARgamma by luciferase reporter gene transactivation assay relative to edaglitazoneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataIC50: 73nMAssay Description:Binding affinity to PPARalpha by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataEC50:  4.60E+3nMAssay Description:Activity at PPARdelta by luciferase reporter gene transactivation assay relative to GW 501516More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50188029(3-(1-((2-(2-chlorophenyl)-5-methyloxazol-4-yl)meth...)
Affinity DataIC50: 251nMAssay Description:Binding affinity to PPARgamma by radio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed