BDBM50185119 2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide::2-[(CYCLOPROPYLCARBONYL)AMINO]-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE::CHEMBL379367

SMILES C1CCc2c(c(c(s2)NC(=O)C3CC3)C(=O)N)C1

InChI Key InChIKey=VATFNEMGBRWLHI-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50185119   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL

LigandBDBM50185119(2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenz...)Copy SMILESCopy InChI

Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankPC cidPC sidPDBSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy Entry DOIPubMed
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TargetSerine/threonine-protein kinase PknG(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidad De Buenos Aires

Curated by ChEMBL

LigandBDBM50185119(2-(cyclopropanecarboxamido)-4,5,6,7-tetrahydrobenz...)Copy SMILESCopy InChI

Affinity DataIC50: 900nMAssay Description:Inhibition of full length Mycobacterium tuberculosis protein kinase G using His-tagged GarA as substrate in presence of [gamma32P] ATP measured after...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/23/2023
Entry Details
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL