BDBM50183566 CHEMBL3822498

SMILES CC1=CC(=CN(C1=O)C)c2ccc(cc2)C(=O)N

InChI Key InChIKey=LCFYRSDVZKRXGW-UHFFFAOYSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50183566   

TargetBromodomain-containing protein 9(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183566(CHEMBL3822498)
Affinity DataKd:  9.10E+3nMAssay Description:Binding affinity to human N-terminal 6His-tagged BRD9 isoform 1 by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 9(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183566(CHEMBL3822498)
Affinity DataIC50: 9.34E+3nMAssay Description:Inhibition of human N-terminal GST-tagged BRD9 isoform 1 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50183566(CHEMBL3822498)
Affinity DataIC50: 3.68E+3nMAssay Description:Inhibition of human N-terminal GST-tagged BRD4-BD1 expressed in Escherichia coli using tetra-acetylated histone H4 measured after 60 mins by AlphaScr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2017
Entry Details Article
PubMed