BDBM50182423 CHEMBL3819367

SMILES Cc1ccccc1-c1cc(Nc2nc(CCCO)cs2)ccc1C

InChI Key InChIKey=KHYLEUBWCWVZDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50182423   

TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182423(CHEMBL3819367)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of Lp-PLA2 in human whole plasma using 2-thio-PAF as substrate preincubated for 15 mins followed by substrate addition measured after 3 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed
TargetPlatelet-activating factor acetylhydrolase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50182423(CHEMBL3819367)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant Lp-PLA2 using 2-thio-PAF as substrate after 20 mins by CPM-based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2017
Entry Details Article
PubMed