BDBM50172075 CHEMBL3808844::US11053225, Positive control (LDC1267)

SMILES CCOc1cn(nc1C(=O)Nc1ccc(Oc2ccnc3cc(OC)c(OC)cc23)c(F)c1)-c1ccc(F)cc1C

InChI Key InChIKey=ISPBCAXOSOLFME-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50172075   

TargetTyrosine-protein kinase receptor UFO(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 19nMAssay Description:Inhibition of AXL in human Hs578t cells by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 4.80nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 4.90nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 68nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 4.80nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 4.90nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 68nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 4.80nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
University of Edinburgh

Curated by ChEMBL
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 4.90nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM50172075(CHEMBL3808844 | US11053225, Positive control (LDC1...)
Affinity DataIC50: 68nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
Go to US Patent