BDBM50167367 (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenylsulfamide::CHEMBL190447::N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]aminosulfonamide::N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]sulfamide

SMILES B1(OC(C(O1)(C)C)(C)C)c2ccc(cc2)NS(=O)(=O)N

InChI Key InChIKey=YQWUJQMJCQBCRA-UHFFFAOYSA-N

Data  16 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50167367   

TargetCarbonic anhydrase 14(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  7.10nMAssay Description:Inhibition of full length human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  8.90nMAssay Description:Inhibition of human carbonic anhydrase 12 catalytic domain preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  48nMAssay Description:Inhibition constant against human recombinant carbonic anhydrase IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  48nMAssay Description:Inhibition of full length human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  75nMAssay Description:Inhibition of full length human carbonic anhydrase 5b preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  81nMAssay Description:Inhibition constant against human recombinant carbonic anhydrase IX catalytic domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  81nMAssay Description:Inhibition of human carbonic anhydrase 9 catalytic domain preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  84nMAssay Description:Inhibition of full length human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  87nMAssay Description:Inhibition of full length human carbonic anhydrase 5a preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 15(Mouse)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  89nMAssay Description:Inhibition of full length mouse carbonic anhydrase 15 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  92nMAssay Description:Inhibition constant against human recombinant carbonic anhydrase IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  92nMAssay Description:Inhibition of full length human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  749nMAssay Description:Inhibition of human carbonic anhydrase 6 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  994nMAssay Description:Inhibition of full length mouse carbonic anhydrase 13 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  8.62E+3nMAssay Description:Inhibition of full length human carbonic anhydrase 4 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Human)
Istituto Di Biostrutture E Bioimmagini-Cnr

Curated by ChEMBL
LigandPNGBDBM50167367((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pheny...)
Affinity DataKi:  8.77E+3nMAssay Description:Inhibition of human carbonic anhydrase 3 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed