BDBM50166643 CHEMBL3799093

SMILES CCN1CCN(c2ccc3c(Nc4cc(CCc5cc(OC)cc(OC)c5)[nH]n4)nc(Cl)nc3c2)CC1

InChI Key InChIKey=KLVPBLIMTASWJW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50166643   

TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166643BDBM50166643(CHEMBL3799093)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of recombinant FGFR2 (unknown origin) using (Glu,Tyr)4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 2(Human)
Chinese Academy of Sciences (Cas)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50166643BDBM50166643(CHEMBL3799093)
Affinity DataIC50: 108nMAssay Description:Inhibition of recombinant FGFR2 in human SNU16 cells assessed as suppression of cell proliferation after 72 hrs by SRB/CCK-8 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2017
Entry Details Article
PubMed