BDBM50164482 CHEMBL3800265

SMILES CC1=C(N2C(=O)C=C(N=C2S1)COc3ccc(cc3)F)[C@@H]4C[C@H]4CO

InChI Key InChIKey=CJDCZVBFZVDWJU-UHFFFAOYSA-N

Data  3 EC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50164482   

TargetGlutamate receptor 2(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164482(CHEMBL3800265)
Affinity DataEC50:  5.40E+3nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flip isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164482(CHEMBL3800265)
Affinity DataEC50:  382nMAssay Description:Positive allosteric modulation of GluN1/GluN2A NMDAR (unknown origin) expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor 2(Human)
Pharmaron-Beijing

Curated by ChEMBL
LigandPNGBDBM50164482(CHEMBL3800265)
Affinity DataEC50:  2.30E+3nMAssay Description:Positive allosteric modulation of human GluA2 AMPAR flop isomer expressed in Dox-inducible cells measured every 5 mins by BD calcium indicator dye ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details Article
PubMed