BDBM50162136 CHEMBL3792924

SMILES CN1C(=CC(=NC1=O)OCc2cc(c(c(c2)F)Oc3ccc(c(c3)C(F)(F)F)Cl)F)N4CCS(=O)(=O)CC4

InChI Key InChIKey=FLCSHCSBIFPQJJ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50162136   

TargetPlatelet-activating factor acetylhydrolase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50162136(CHEMBL3792924)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF as substrate measured for 10 mins by plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-activating factor acetylhydrolase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50162136(CHEMBL3792924)
Affinity DataKd:  185nMAssay Description:Binding affinity to human Lp-PLA2 by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)