BDBM50159140 CHEMBL3785648

SMILES CCc1c(c([nH]c1C(=O)NC)C)C(=O)C

InChI Key InChIKey=LCSLEHAEHBSCSA-UHFFFAOYSA-N

Data  9 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50159140   

TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  6.80E+3nMAssay Description:Binding affinity to partial length human BRD4 bromodomain 1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  3.00E+4nMAssay Description:Binding affinity to partial length human BRPF1 by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2017
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  1.81E+4nMAssay Description:Binding affinity to human His-Tev tagged CBP expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetHistone acetyltransferase p300(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to human His-Tev tagged EP300 expressed in bacterial expression system incubated for 30 mins by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.40E+4nMAssay Description:Binding affinity to BRD4 bromo domain 1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPeregrin(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.30E+4nMAssay Description:Binding affinity to BRPF1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCREB-binding protein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCREB-binding protein(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  1.81E+4nMAssay Description:Binding affinity to CBP (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetHistone acetyltransferase p300(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50159140(CHEMBL3785648)
Affinity DataKd:  2.26E+4nMAssay Description:Binding affinity to P300 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed