BDBM50157493 4-[1-allyl-7-(trifluoromethyl)-1H-indazol-3-yl]benzene-1,3-diol::CHEMBL222501::WAY-169916

SMILES Oc1ccc(-c2nn(CC=C)c3c(cccc23)C(F)(F)F)c(O)c1

InChI Key InChIKey=ZDUDMCQPFKPISO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157493   

TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157493(WAY-169916 | 4-[1-allyl-7-(trifluoromethyl)-1H-ind...)
Affinity DataIC50: 1.30E+3nMAssay Description:Displacement of [3H]E2 from ERalpha ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157493(WAY-169916 | 4-[1-allyl-7-(trifluoromethyl)-1H-ind...)
Affinity DataIC50: 93nMAssay Description:Activity at human ERalpha expressed in HAECT1 cells assessed as inhibition of NF-kappaB transcriptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157493(WAY-169916 | 4-[1-allyl-7-(trifluoromethyl)-1H-ind...)
Affinity DataIC50: 106nMAssay Description:Displacement of [3H]E2 from ERbeta ligand binding domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed