BDBM50156294 CHEMBL3781415

SMILES Nc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccncc2)n1

InChI Key InChIKey=XXSDLQLNIVFIJI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50156294   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human VPS34 using L-alpha-phosphatidylinositol as substrate incubated for 10 mins by luminescence based ATP detection assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 12nMAssay Description:Inhibition of VPS34 in human U2OS cells incubated for 2 hrs by GFP-FYVE reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 18nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2018
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 0.0180nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156294(CHEMBL3781415)
Affinity DataIC50: 18nMAssay Description:Inhibition of Vps34 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed