BDBM50150920 2-AMINOTHIAZOLINE::4,5-dihydrothiazol-2-amine::CHEMBL362148::Thiazolidin-(2E)-ylideneamine

SMILES C1CSC(=N1)N

InChI Key InChIKey=REGFWZVTTFGQOJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150920   

TargetNitric oxide synthase, endothelial(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50150920(4,5-dihydrothiazol-2-amine | 2-AMINOTHIAZOLINE | T...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory activity against Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50150920(4,5-dihydrothiazol-2-amine | 2-AMINOTHIAZOLINE | T...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibitory activity against Neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50150920(4,5-dihydrothiazol-2-amine | 2-AMINOTHIAZOLINE | T...)
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50150920(4,5-dihydrothiazol-2-amine | 2-AMINOTHIAZOLINE | T...)
Affinity DataKi:  410nMAssay Description:Inhibition of nNOS assessed as conversion of L-[3H]arginine to L-[3H]citrullineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed