BDBM50149294 CHEMBL3769578

SMILES CC(C)(C)c1ccc(cc1)CC[C@@](CC(=O)O)(C(=O)O)O

InChI Key InChIKey=QNFWRHKLBLSSPB-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50149294   

TargetSolute carrier family 13 member 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of NaCT in human hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 13 member 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NaDC1 (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSolute carrier family 13 member 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NaDC3 (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetSolute carrier family 13 member 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 501nMAssay Description:Inhibition of NaCT (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 13 member 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of NaCT in human hepatocytes assessed as [14C]-citrate uptake after 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 13 member 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 501nMAssay Description:Inhibition of NaCT (unknown origin) expressed in HEK293 cells assessed as inhibition of [14C]citrate uptake by microbeta plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 13 member 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50149294(CHEMBL3769578)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of SLC13A5 in human hepatocyte cells assessed as reduction in citrate uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)