BDBM50147093 6-Carbamimidoyl-4-(pyrimidin-2-ylamino)-naphthalene-2-carboxylic acid (4-aminomethyl-phenyl)-amide::6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-4-(PYRIMIDIN-2-YLAMINO)-2-NAPHTHAMIDE::CHEMBL104166::N-(4-(aminomethyl)phenyl)-6-carbamimidoyl-4-(pyrimidin-2-ylamino)-2-naphthamide

SMILES c1cnc(nc1)Nc2cc(cc3c2cc(cc3)C(=N)N)C(=O)Nc4ccc(cc4)CN

InChI Key InChIKey=CSWQJKHBMACTGB-UHFFFAOYSA-N

Data  7 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50147093   

TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataIC50: 0.620nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards Urokinase-type plasminogen activator (urokinase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataKi:  0.631nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine protease 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataKi:  20nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKallikrein-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataKi:  40nMAssay Description:Binding affinity towards P-kallikreinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataKi:  150nMAssay Description:Binding affinity against plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataKi:  680nMAssay Description:Binding affinity towards tissue type plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50147093(6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENY...)
Affinity DataKi:  940nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed