BDBM50144936 CHEMBL1090::VIDARABINE::adenine arabinoside

SMILES c1nc(c2c(n1)n(cn2)[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N

InChI Key InChIKey=OIRDTQYFTABQOQ-UHFFFAOYSA-N

Data  1 KI  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144936   

TargetGlycogen synthase kinase-3 beta(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM50144936(adenine arabinoside | CHEMBL1090 | VIDARABINE)
Affinity DataEC50: >3.00E+5nMAssay Description:Keywords: GSK3beta, dose response, kinase, inhibition, HTS Assay Overview: The glycogen synthase kinase-3 beta (GSK-3b) is a known master regulator f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2011
Entry Details
PCBioAssay
TargetDipeptidyl peptidase 4(Human)
Instituto De Qu£Mica M£Dica (Csic)

Curated by ChEMBL
LigandPNGBDBM50144936(adenine arabinoside | CHEMBL1090 | VIDARABINE)
Affinity DataIC50: 62nMAssay Description:Inhibition of human DPP4 from human Caco-2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144936(adenine arabinoside | CHEMBL1090 | VIDARABINE)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition HCV RNA replicationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144936(adenine arabinoside | CHEMBL1090 | VIDARABINE)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAdenosylhomocysteinase(Mouse)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50144936(adenine arabinoside | CHEMBL1090 | VIDARABINE)
Affinity DataKi:  3.00E+4nMAssay Description:Activity determined in mouse liver S-adenosyl-L-homocysteine hydrolase and expressed as KI values.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed