BDBM50143216 CHEMBL3759079

SMILES Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)nc1

InChI Key InChIKey=YFPYQMFBXQUNHH-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50143216   

TargetVascular endothelial growth factor receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human KDR using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human ABL using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human ErbB2 using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human EPH-A2 using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human c-Src using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human Flt-3 using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human Flt-1 using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human EGFR using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetMacrophage-stimulating protein receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human Ron using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human PDGFR-beta using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human PDGFR-alpha using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human IGF1R using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human FGFR1 using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase Mer(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human Mer using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor TYRO3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human TyrO3 using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50143216(CHEMBL3759079)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human Axl using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2017
Entry Details Article
PubMed