BDBM50132151 CHEMBL101683::N-(4-Chloro-phenyl)-2-[(pyridin-4-ylmethyl)-amino]-benzamide::N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benzamide::N-(4-chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide

SMILES c1ccc(c(c1)C(=O)Nc2ccc(cc2)Cl)NCc3ccncc3

InChI Key InChIKey=GGPZCOONYBPZEW-UHFFFAOYSA-N

Data  1 KI  10 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50132151   

TargetVascular endothelial growth factor receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 180nMAssay Description:Inhibition of vascular endothelial growth factor receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInsulin-like growth factor 1 receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 240nMAssay Description:Inhibition of Proto-oncogene tyrosine-protein kinase KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Met proto-oncogene tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cyclin-dependent kinase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 20nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataIC50: 20nMAssay Description:Inhibition of KDR by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50132151(N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benz...)
Affinity DataKi:  15nMAssay Description:Inhibition of phosphorylated-Kdr after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed