BDBM50130583 5H-Benzo[c][1,8]naphthyridin-6-one::CHEMBL110381

SMILES c1ccc2c(c1)-c3cccnc3NC2=O

InChI Key InChIKey=YLSBDRGLLZDAKB-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130583   

TargetPoly [ADP-ribose] polymerase 1(Human)
Guilford Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130583(5H-Benzo[c][1,8]naphthyridin-6-one | CHEMBL110381)
Affinity DataIC50: 311nMAssay Description:Inhibitory activity against Poly (ADP-ribose) polymerase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50130583(5H-Benzo[c][1,8]naphthyridin-6-one | CHEMBL110381)
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of aurora-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)