BDBM50128058 ALLYL-{6-[3-(4-BROMO-PHENYL)-1-METHYL-1H-INDAZOL-6-YL]OXY}HEXYL)-N-METHYLAMINE::Allyl-{6-[3-(4-bromo-phenyl)-1-methyl-1H-indazol-6-yloxy]-hexyl}-methyl-amine::CHEMBL115497::CHEMBL66424::N-allyl-6-(3-(4-bromophenyl)-1-methyl-1H-indazol-6-yloxy)-N-methylhexan-1-aminium

SMILES Cn1c2cc(ccc2c(n1)c3ccc(cc3)Br)OCCCCCC[N@](C)CC=C

InChI Key InChIKey=FNZKIJOTNKEJBF-UHFFFAOYSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50128058   

TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 19.6nMAssay Description:Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSqualene--hopene cyclase(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 289nMAssay Description:Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldariusMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetLanosterol synthase ERG7(Baker's yeast)
Università

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 290nMAssay Description:Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCycloartenol synthase(Mouse-ear cress)
Università

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 19.6nMAssay Description:In vitro inhibition of human 2,3-oxidosqualene cyclase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Albert-Ludwigs-University of Freiburg

Curated by ChEMBL
LigandPNGBDBM50128058(CHEMBL115497 | Allyl-{6-[3-(4-bromo-phenyl)-1-meth...)
Affinity DataIC50: 19nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed