BDBM50126669 (2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2,4-DICHLORO-BENZOYL)-AMINO]-3-PHENYL-PROPIONIC ACID::(S)-2-(N-((5-(benzofuran-2-yl)thiophen-2-yl)methyl)-2,4-dichlorobenzamido)-3-phenylpropanoic acid::(S)-2-[(5-Benzofuran-2-yl-thiophen-2-ylmethyl)-(2,4-dichloro-benzoyl)-amino]-3-phenyl-propionic acid::2-[(5-Benzofuran-2-yl-thiophen-2-ylmethyl)-(2,4-dichloro-benzoyl)-amino]-3-phenyl-propionic acid::CHEMBL278785

SMILES OC(=O)[C@H](Cc1ccccc1)N(Cc1ccc(s1)-c1cc2ccccc2o1)C(=O)c1ccc(Cl)cc1Cl

InChI Key InChIKey=YBULOUKTPCHXAL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126669   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126669(2-[(5-Benzofuran-2-yl-thiophen-2-ylmethyl)-(2,4-di...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
University of Wollongong

Curated by ChEMBL
LigandPNGBDBM50126669(2-[(5-Benzofuran-2-yl-thiophen-2-ylmethyl)-(2,4-di...)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibitory constant against hepatitis C virus NS3 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed