BDBM50123046 2-[4-(4-Hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-phenyl]-2H-[1,2,4]triazine-3,5-dione::CHEMBL125381::[4-(4-HYDROXY-3-ISOPROPYL-PHENOXY)-3,5-DIMETHYL-PHENYL]-6-AZAURACIL

SMILES Cc1cc(cc(c1Oc2ccc(c(c2)C(C)C)O)C)N3C(=O)NC(=O)C=N3

InChI Key InChIKey=RXQAVKWRCZYGMV-UHFFFAOYSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50123046   

TargetThyroid hormone receptor beta(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50123046([4-(4-HYDROXY-3-ISOPROPYL-PHENOXY)-3,5-DIMETHYL-PH...)
Affinity DataKi:  0.0300nMAssay Description:Effective concentration binding towards TR-beta-1 in E25B2 cells (agonistic activity)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)