BDBM50120436 CHEMBL3617972

SMILES CC1=C([C@H](NC(=O)N1c2cccc(c2)C(F)(F)F)c3ccc(cc3S(=O)(=O)C)C#N)C#N

InChI Key InChIKey=WQASVWJQEKONLG-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50120436   

TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120436(CHEMBL3617972)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human neutrophil elastase using MeOSuc-AAPV-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeutrophil elastase(Human)
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50120436(CHEMBL3617972)
Affinity DataIC50: 0.540nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)