BDBM50111384 CHEMBL3604794
SMILES Oc1c(F)cc(cc1F)-c1cnccc1-c1ccc(cc1)N1CCOCC1
InChI Key InChIKey=YUYJEQHNWKQNBT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50111384
TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant Histidine-tagged RSK2 using biotin-AGAGRSRHSSYPAGT-OH as substrate preincubated for 30 mins followed by ATP and subst...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Mouse)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataEC50: 210nMAssay Description:Inhibition of RSK2 in mouse BAF cells expressing activated FGFR assessed as reduction of YB1 phosphorylation at Ser102 by electochemiluminescence ass...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of RSK2 (unknown origin) assessed as reduction in YB1 transmembrane phosphorylationMore data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Human)
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of RSK2 (unknown origin)More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-2(Human)
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of RSK3 (unknown origin)More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-1(Human)
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of full length recombinant His-tagged human RSK1 expressed in baculovirus expression system using biotin-labelled AGAGRSRHSSYPAGT-OH as su...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Novartis Institutes For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of full length recombinant His-tagged human RSK2 expressed in baculovirus expression system using biotin-labelled AGAGRSRHSSYPAGT-OH as su...More data for this Ligand-Target Pair
TargetRibosomal protein S6 kinase alpha-2(Human)
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
University of Colorado Anschutz Medical Campus
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full length recombinant GST-tagged human RSK3 expressed in insect cell using biotin-labelled AGAGRSRHSSYPAGT-OH as substrate in presenc...More data for this Ligand-Target Pair