BDBM50105106 1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL114484

SMILES Cc1ccc(CN2CCC(CC2)n2c3ccccc3[nH]c2=O)c(Cl)c1

InChI Key InChIKey=KTQASNDGWLUTPN-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50105106   

LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 1.34E+3nMAssay Description:Binding affinity against L-type calcium channel verapamil siteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of ligand binding to human delta opioid receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 480nMAssay Description:Inhibition of human dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 1.57E+3nMAssay Description:Binding affinity against muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 154nMAssay Description:Inhibition of human dopamine receptor D3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of human dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 1.78E+3nMAssay Description:Binding affinity against M1 muscarinic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 849nMAssay Description:Inhibition of human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human ORL1 orphanin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 270nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50: 16nMAssay Description:Binding affinity against mu opiate receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed